Dosage form: Single dose intramammary infusion
Composition: Each 10 gr Syringe contains
Cloxacillin (Benzathine) 500 mg
Sulfadimidin (Sodium) 750 mg
rimethoprim 125 mg
Oil base up to 10 gr
Target species: Cattle
Cloxacillin is a semi-synthetic antibiotic from betalactam group that has activity against the following major pathogens associated with mastitis; Staphylococcus spp., Micrococcus spp., Streptococcus agalactiae, Corynebacterium spp. and other bacteria during the dry period in cows.
Sulfadimidin Sodium is effective against Gram-positive and Gram-negative bacteria including Streptococcus, Staphylococcus, bacillus anthracis, clostridium tetani, clostridium perfringens, Escherichia coli, salmonella, pasteurella, chlamydia, nocardia and some protozoa such as coccidia and Toxoplasma spp.
Trimethoprim binds to dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). THF is an essential precursor in the thymidine synthesis pathway and interference with this pathway inhibits bacterial DNA synthesis.
Indications: Treatment or prevention of mastitis occurring in the dry period.
Dosage and Administration: For intramammary administration only. The contents of one syringe should be infused into each quarter via the teat canal immediately in drying period. Before infusion, the teat should be thoroughly cleaned and disinfected and care should be taken to avoid contamination of the injector nozzle. After infusion, massage the contents up into the udder.
Do not use in lactating cows.
Animals intended for human consumption should not be slaughtered until 28 days after the last treatment.
Store below 25°C and protect from light and freezing.
Each box contains 24 syringes