果糖二磷酸钠口服溶液 eShow Global
果糖二磷酸钠口服溶液

北京华靳制药有限公司

Beijing Huajin Pharmaceutical Co., Ltd.

China    City:Beijing

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Product Details

Package Insert of Fructose Sodium Diphosphate Oral Solution 

 

Please read the instruction carefully and use prescription drugs under the guidance 

of practicing doctors. 

 

【Drug Name】 

Generic Name: Fructose Sodium Diphosphate Oral Solution 

Trade Name: Ruianji 

English Name: Fructose Sodium Diphosphate Oral Solution 

Chinese Pinyin: Guotang Erlinsuanna Koufurongye 

【Composition】 

The main ingredient of this product is fructose sodium diphosphate 

Chemical Name: fructose 1,6-diphosphate trisodium salt 

Chemical Structure: 

 

Molecular Formula: C6H11Na3O12P2 

Molecular Weight: 406.06 


【Description】 

This product is a colorless to slightly yellow clear liquid, sweet. 

【Indications】 

This product is used to improve the symptoms of angina caused by 

coronary heart disease, acute myocardial infarction, arrhythmia, 

myocardial ischemia in heart failure and adjuvant therapy for viral 

myocarditis. And it also can be used to improve the  symptoms of 

cerebral anoxia caused by cerebral infarction, cerebral haemorrhage 

and so on. 

【Specification】 

10ml:1g, on C6H11Na3O12P2 basis. 

【Dosage and Administration】 

Orally, 1~2g(10~20ml)every time, 2~3 times a day 

【adverse Reactions】 

Mainly for mild symptoms of the digestive system, such as distention, 

nausea, abdominal burning sensation, loose stool. It was generally 

tolerable by patients without discontinuation. 

【Contraimdication】 

This product should not be used in patients with hyperphosphatemia 

and renal failure. 

【Precautions】 

1. A small amount of material may be precipitated out at lower 

temperatures, if the liquid is clear, this products can be used 

normally without influencing the clinical effect.  

2. The product should be taken after a meal for the patients suffering 

from a severe peptic ulcer. 

3. The product should be used alone and not be dissolved in other 

products, especially in alkaline solutions and calcium salts. Do not 

take if the seal is loose seal or the liquid is muddy. 

【Medication for Pregnant and Lactant Women】 

None known.  

【Medication for Children】 

None known. 

【Drug Use in Older adults】 

None known. 

【Drug Interactions】 

The product should be used alone and not be dissolved in other 

products, especially in alkaline solutions and calcium salts. 

【Overdosage】 

No research datas about overdose are available at present. 

【Pharmacology and Toxicology】 

The main ingredient of this product can regulate the activities of 

enzymes in glucose metabolism, as an cell metabolite which exists in 

human body. It is reported that ectogenic fructose sodium diphosphate 

can increase the concentrations of adenosine triphosphate and 

phosphocreatine in cells and also can accelerate K+ flowing into the cell 

by activating phosphofructokinase and pyruvate kinase, and it can be 

beneficial to both energy metabolism and glucose utilization in cells 

under the conditions of hypoxia and ischemia, thereby alleviating 

ischemic myocardium injury. 

【Pharmacokinetics】 

Lack of the pharmacokinetic parameters in humans and in animals. 

【Storage】 

Seal tightly and keep it under 30℃. 

【Package】 

Tube vial, 10ml per tube: 6 tubes per box; 10 tubes per box; 20 tubes 

per box 

【Shelf Life】 

24 months 

【Executive Standard】 

WS1-(X-244)-2003Z-2011 

【Approval Number】 

SFDA approval number H19990353 

【Manufacturer】 

Name: Beijing Huajin Pharmaceutical CO., Ltd 

Address: No.2 Shuangqiao East Road, Chaoyang District, Beijing 

Postal Code: 100121 

Tel: (010)52088820 

Customer Service Tel: 800-810-1916 

Fax: (010)5208876 


果糖二磷酸钠口服溶液

 产品简介:果糖二磷酸钠是存在于人体内的细胞代谢物,能调节葡萄糖代谢中多种酶系的活性。外源性的果糖二磷酸钠,能通过激活磷酸果糖激酶和丙酮酸激酶的活性,使细胞内三磷酸腺苷和磷酸肌酸的浓度增加,促进钾离子内流,有益于缺血、缺氧状态下细胞的能量代谢和葡萄糖利用,从而可使缺血心肌减轻损伤。

 适应症:用于改善冠心病的心绞痛、急性心肌梗死、心律失常和心力衰竭的心肌缺血以及病毒性心肌炎的辅助治疗。亦可用于改善脑梗死和脑出血等引起的脑缺氧状态。

 规格:10ml:1g*6支  10ml:1g*10支  10ml:1g*20支

 用法用量:  

口服

成人:一次10-20ml(1-2支),Tid

儿童:<1岁:一次10ml(1支),Qd

1-2岁:一次10ml(1支),Bid

2-7岁:一次10ml(1支),Tid

≥7岁:一次20ml(2支),Tid

 应用科室:儿科、心内科、心外科、神经内科、老年科、急诊、ICU等心肌功能相关疾病科室。

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China      2019-08-20
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